Meet The Prions: Abeta & Tau Are The Molecular Basis of Alzheimer's [Explainer Video] from and prion com Watch Video

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⏲ Duration: 1 min 55 sec
✓ Published: 26-Jan-2018
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Episode 6 of BrainStorm Live - Amprion CEO Dr. Russ Lebovitz explains the molecular basis and specific Prions' structures underlying Alzheimer's disease. The bad players are: Abeta and Tau. Both of these Prions or misfolded proteins are proteins gone rogue. Amprion's breakthrough Prion Early Detection Testing℠ detects these rogue proteins in people who are at-risk with Alzheimer's prior to any clinical symptoms.nn============nJoin us and be the first to know as soon as Amprion’s breakthrough

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Episode 5 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz discusses the role Prions (misfolded proteins) play in neurodegenerative diseases, including Alzheimer's and Parkinson's. What's causing the diseases? It's the misfolding of normal brain proteins into unusual shapes that stick to one another forming aggregates of various sizes. These aggregated forms of Prions are toxic to nerve cells and ultimately cause irreversible damage and cell death. Amprion's breakthrough Prion Early Detectio
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Episode 11 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz talks about the company's breakthrough Prion Early Detection Science℠which accurately detects the soluble Prion aggregates in Alzheimer's and Parkinson's prior to any clinical symptoms. We believe our Prion Early Detection Testing will pave an innovative pathway to reinvent drug development for successful treatments for Alzheimer's and Parkinson's. nn============nJoin us and be the first to know as soon as Amprion’s breakthrou
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Episode 12 of BrainStorm Live - Amprion's CEO Dr. Russ Lebovitz explains the key elements that drive the progression of Alzheimer’s, Parkinson's and other neurodegenerative diseases: self-propagating soluble misfolded protein aggregates. Also known as Prions, they are composed of misfolded proteins of Abeta, Tau and Synuclein. Amprion’s innovative Prion Early Detection Science℠ tracks these Prions in biological fluids and tissues in very low concentration. Early detection of the molecular
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Moon, et al. “Prion peptide-mediated calcium level alteration governs neuronal cell damage through AMPK-autophagy flux.” Cell Communication and Signaling (2020)nnRead the article: https://doi.org/10.1186/s12964-020-00590-1nnVideo produced by https://www.researchsquare.com/researchers/videos
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Episode 3 of BrainStorm Live - Amprion’s CEO Dr. Russ Lebovitz talks about the earliest molecular changes associated with Alzheimer's and Parkinson's. These changes involve the formation of small soluble aggregates of misfolded proteins within the brain. Known as Prions, these soluble aggregates can replicate slowly within the brain by causing other normal proteins to misfold, forming new Prions. They can also move from cell to cell. These Prions have long incubation period, and are highly des
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