MCM complexes are barriers that restrict cohesin-mediated loop extrusion from hi in austrian Watch Video
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⏲ Duration: 15 min 35 sec ✓ Published: 17-Sep-2021
Description: Presented by: Bart Dequeker, PhD StudentnnInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austriannn-----nnEukaryotic genomes are compacted into loops and topologically associating domains (TADs), which contribute to transcription, recombination and genomic stability. Cohesin extrudes DNA into loops that are thought to lengthen until CTCF boundaries are encountered. Little is known about whether loop extrusion is impeded by DNA-bou
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