_clinical-trial-data-on-treatment-of-chronic-lymphocytic-leukaemia-with-pci-32765.jpg "Clinical trial data on treatment of chronic lymphocytic leukaemia with PCI-32765 from lymphocyte Video Screenshot Preview")
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⏲ Duration: 4 min 69 sec
✓ Published: 23-Jan-2018
✓ Published: 23-Jan-2018
Description:
Dr Susan O’Brien presented data on PCI-32765 at ASH 2011 and discussed some of the details with ecancertv. Dr O’Brien explained that if the drug can ligate the B cell receptor, then this could be beneficial by preventing signals going to the cell nucleus. nn nnThe clinical relevance is that PCI-32765 targets a specific mutation in patients and rapidly reduces lymph node mass with very little toxicity and without being myelosuppressive; however, the drug increases lymphocyte count. Over tim
Dr Susan O’Brien presented data on PCI-32765 at ASH 2011 and discussed some of the details with ecancertv. Dr O’Brien explained that if the drug can ligate the B cell receptor, then this could be beneficial by preventing signals going to the cell nucleus. nn nnThe clinical relevance is that PCI-32765 targets a specific mutation in patients and rapidly reduces lymph node mass with very little toxicity and without being myelosuppressive; however, the drug increases lymphocyte count. Over tim
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